Report says, this would be the third of such "de-escalation zone" put in place since July after talks between powers backing and opposing the Syrian government.
The others cover parts of south-western Syria and the outskirts of Damascus.
Syria's war has raged since 2011 but fighting has become more patchy amid a series of truce deals in recent months.
Russian Defence Ministry spokesman Igor Konashenkov said the latest ceasefire was agreed with the moderate Syrian opposition and covered an area encompassing more than 147,000 people.
He said Russia would set up two checkpoints and three observation posts along the truce lines on today.
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